PROTECTIVE EFFECT OF GRAPE SEEDS POWDER AND OIL AGAINST HYPERCHOLESTEROLEMIA IN RATS
نویسندگان
چکیده
منابع مشابه
Protective effect of red grape seeds proanthocyanidins against induction of diabetes by alloxan in rats.
It has been documented that impaired homeostasis in diabetes mellitus is associated with increased production of reactive oxygen species and depletion of the antioxidant defense systems. Natural grape seed proanthocyanidins (GSP) are potent free radical scavengers and hence provide significant protection against oxidative stress. Accordingly, the present study focused on investigating the possi...
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Oxidative stress with subsequent production of reactive oxygen species has been postulated as one of the mechanisms of naphthalene toxicity. In the present study, the effect of oral administration of the natural antioxidant and free radical scavenger, proanthocyanidins present in grape seeds (GSP, 10 or 50 mg kg, p.o.), has been investigated in rats following the concomitant administration of n...
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Background: Methotrexate (MTX) is an anti-metabolite drug used in the treatment of many cancers and autoimmune diseases. Methods: This study investigated the protective effect of flaxseed oil, sesame seed oil, and their mixture on the MTX-induced hepatorenal toxicity. Thirty rats divided into five groups of: normal control, MTX control, and flaxseed oil, sesame seed oil, and the mixture groups...
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Objective: This study was done on 40 male wistar rats to evaluate the curative and protective effect of grape seeds extract on oxidative damage, inflammatory and apoptotic insult on lung tissue induced by cadmium chloride toxicity. Materials and Methods: The rats were classified to control group (group I), cadmium chloride group (group II), grape seeds extract group (group III) and mixture of g...
متن کاملThe protective effects and genetic pathways of thorn grape seeds oil against high glucose-induced apoptosis in pancreatic β-cells
BACKGROUND Excessive apoptosis of β-cell is closely related to diabetes mellitus. Chronic exposure to high glucose causes β-cell dysfunction and apoptosis in diabetes. Thorn grape (Vitis davidii Foex.) has been used to treat diabetes in Traditional Chinese medicine for many years. In our previous research, thorn grape seeds oil (TGSO) showed promising anti-diabetic effects in animal models. How...
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ژورنال
عنوان ژورنال: Journal of Food and Dairy Sciences
سال: 2015
ISSN: 2090-3731
DOI: 10.21608/jfds.2015.50103